Name: chitosan powder
Brand: Joyous Pellets Supplement raw materials, cosmetic ingredients, weight
Availability: InStock
Rating: 5 (1 reviews)

Chitosan is the product of N-deacetylation of chitin. Chitin (chitin), chitosan, and cellulose have similar chemical structures. Chitin and chitosan are biodegradable and cell-friendly. It has many unique properties such as sex and biological effects, especially chitosan containing free amino groups, which is the only alkaline polysaccharide among natural polysaccharides. Joyous' chitosan is widely used in various fields of medicine

Product Name

chitosan

Specification

99%

CAS No

9012-76-4

Appearance

white powder

Chemical Formula

（C6H11NO4）n

Packaging

25kg cardboard drum

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Desciption

Product information
What is chitosan powder?
There are large amounts of chitin in the shells of marine arthropods such as shrimps and crabs, the shells of insects, the cell membranes of fungi and algae, the shells and bones of molluscs, and the cell walls of higher plants. Chitin is widely distributed in nature, and its reserves are second only to cellulose. It is the second largest natural polymer. The amount of chitin biosynthesized every year is about 10 billion tons. It is a recyclable renewable resource that is inexhaustible and used. Inexhaustible, these natural polymers are mainly distributed in coastal areas, such as India, Poland, Japan, the United States, Norway and Australia.
Chitin was first discovered in mushrooms in 1811 by Professor H. Bracolmot, who studied the history of natural sciences in France, and named it Fungine. In 1823, another French scientist Ogier isolated the same substance from the wing sheaths of crustacean insects and named it chitin; in 1859, French scientist C. Rouget soaked chitin in a concentrated KOH solution and boiled it After a period of time, it was taken out and washed and found to be soluble in organic acids; in 1894, the German Ledderhose confirmed that the modified chitin prepared by Rouget was chitin with part of the acetyl group removed, and named it chitosan, which means chitosan. ; In 1939, Haworth obtained an uncontroversial synthesis method and determined the structure of chitin; in 1936, the American Rigby obtained a series of authorized patents on chitin/chitosan, describing the synthesis of chitin from shrimp shells and crab shells. Methods for isolating chitin from shells, methods for preparing chitin and chitin derivatives, and methods for preparing chitosan solutions, chitosan films and chitosan fibers; in 1963, Budall proposed that chitin exists in three crystal forms; In the 1970s, research on chitin increased; in the 1980s and 1990s, research on chitin/chitosan entered its heyday.
Chitosan, also known as deacetylated chitin, soluble chitin, and polyglucosamine, is an off-white powder, odorless and tasteless. This product is slightly soluble in water and almost insoluble in ethanol. Chitosan is a cationic polyamine with a high charge density at pH < 6.5 (so it can adsorb to anionic surfaces and chelate metal ions). Chitosan is a linear polyelectrolyte with active hydroxyl and amino groups (can undergo chemical reactions and form salts).

Joyous chitosan powder specification

Terms	Standard	Terms	Standard
Product Name	chitosan	Appearance	white powder
Assay	98%	Loss on Drying	≤2%
Total Heavy Metals	≤10 ppm	Ash	≤2%
As	≤0.5ppm	Total Plate Count	≤750 cfu/g
Pb	≤0.5ppm	Yeast and Mold	≤100 cfu/g
Cd	≤0.5ppm	Coliforms	Negative
Hg	≤0.1ppm	E.Coli	Negative
Packing	Pack in 25kgs paper-drums, inner by double plastic bag	Shelf life	24 months under the above condition, and in its original package

What are the antibacterial properties and application areas of chitosan?
The fact that chitosan has strong antifungal properties is well known. Alen et al.’s antibacterial experiments on 46 species of fungi found that chitosan has an inhibitory effect on 32 species of fungi, including Phytophthora, Neurospora, and Nematodes. Generally, when the concentration of chitosan reaches 100 μg/mL, antifungal properties can be demonstrated, and the antifungal properties are inversely proportional to the size of chitosan particles. The degree of polymerization of chitosan has a great influence on its antifungal property. As the degree of polymerization decreases, the types of fungi that chitosan can inhibit decrease, but the degree of inhibition increases. Kendra et al. also found that heptameric chitosan has the strongest antifungal activity.
Chitosan has good inhibitory effects on Escherichia coli, Pseudomonas fluorescens, Staphylococcus aureus, Bacillus subtilis, etc., and can also inhibit physiological changes in fresh food. Chitosan is naturally non-toxic and is suitable for the preservation of acidic and low-protein foods. It can agglomerate when encountering polymers and ionic complexes. For example, for the preservation and preservation of fruits, the dosage is 0.1% acetic acid + 0.05%-0.1% chitosan. [3]
Chitosan derivatives also have good antibacterial properties, even stronger than chitosan.

Application direction
Chitosan has been discovered for more than 100 years, and many people are studying it. It is widely used in agriculture, food, medicine, and industry.
Uses of Chitin and Its Derivatives A large number of studies have shown that chitin and its derivatives have film-forming properties, spinnability, anticoagulant properties, and the ability to promote wound healing. Therefore, chitin and its derivatives are widely used in many fields such as food, biochemistry, medicine, daily cosmetics, and sewage treatment. Joyous summarizes the main uses of chitosan as follows.
Applications in the food industry
Chitosan can be used as a binder, moisturizer, clarifier, filler, emulsifier, polishing agent and thickening stabilizer in the food industry; as a functional oligosaccharide, it can lower cholesterol and improve the body's immunity. Enhance the body's ability to resist disease and infection, and especially has strong anti-tumor effects. Because of its rich resources and high application value, it has been widely developed and used. In industry, chitosan is extracted by enzymatic or acid hydrolysis of shrimp skin or crab shells.
1.As an immobilized enzyme carrier
The chitosan acetic acid solution is sprayed into the alkali solution for solidification. After separation and regeneration, chitosan fine particles can be used as a carrier for immobilized enzymes. The enzymes immobilized by chitosan can be used for sugar making, wine making, and vinegar making. Protein hydrolysis and other biological preparation engineering.
2. Used as food additives
As a food thickener and stabilizer, microcrystalline chitosan can be used in the production of mayonnaise, peanut butter, sesame paste, canned polenta, cream substitutes and other condiments. Usually, vinegar often produces precipitation after being left for a long time, which is mainly caused by the metals in it. It is caused by the formation of macromolecular complexes between ions and phenolic acids such as tannins. Vinegar treated with chitin and chitosan did not precipitate after being stored for one year. When producing soy sauce, adding an appropriate amount of chitosan can remove protein and prevent precipitation. Adding a small amount of chitosan to miso can appropriately reduce the amount of salt added, and the product will not deteriorate after long-term storage.
3. Used as food packaging film
Chitosan, starch and water are mixed evenly to form a film. After drying, it is treated with alkali solution to make a chitosan-starch synthetic food packaging film. This film is non-toxic, edible, oil-resistant, and insoluble in cold and heat. Water, high tensile strength, can be used to package solid, semi-solid and liquid food. The film can automatically biodegrade, so there is no white environmental pollution.
4. Used for food preservation and preservation
Chitosan can be used to preserve vegetables, meat products, seafood, starch, soy products, and eggs, milk and soy products.
Due to the influence of physiological maturation after picking, fruits and vegetables will soften, resulting in a decrease in hardness, making transportation difficult, a decrease in quality and nutritional value, and a weakening of the resistance to bacteria. Therefore, how to preserve fruits and vegetables has long attracted people's attention. Chitosan has film-forming properties and is not only harmless to the human body, but also has physiological health care effects. Its protective effect on fruits and vegetables is increasingly recognized by people. Covering the surface of fruits and vegetables with chitosan can reduce the transpiration of fruits and vegetables, and has a certain selective permeability effect on gases, which can prevent external O2 from entering the membrane, increase the content of CO2 in the fruit and vegetable tissues and reduce the escape of ethylene, thereby reducing The respiratory metabolism intensity of fruits and vegetables slows down the ripening of fruits and vegetables to achieve the purpose of preservation.
Chitosan has an obvious preservation effect on chilled pork, and the higher the deacetylation degree of chitosan, the better the preservation effect on chilled meat. A 1% chitosan solution dissolved in 1% acetic acid can extend the shelf life of chilled meat to 1 week, and the sensory quality of the chilled meat is good; the preservation effect of 2.5% water-soluble chitosan solution is slightly lower than that of 1% acid-soluble chitosan solution Chitosan, but water-soluble chitosan-treated chilled meat samples had no sour taste at all and had good sensory quality.
Chitosan is an excellent natural antibacterial antioxidant for seafood rich in unsaturated fatty acids. Chitosan of different molecular weights prepared from snow crabs, with a concentration of 50-200mg/kg, can effectively control the cooking process of cod meat. Lipids oxidize during the cooking process, and the higher the concentration, the stronger the antioxidant capacity.
Applications in daily chemicals
Chitosan is non-toxic, odorless, and has antibacterial effects. When used in cosmetics, it can improve the film-forming properties of the product and has antibacterial and moisturizing functions without causing any allergic irritation. For example, if a hydroxypropyl ammonium chloride group is introduced into the chitosan molecule, the resulting chitosan hydroxypropyltrimethylammonium chloride can enhance the hydration capacity of chitosan, improve its hygroscopic and moisturizing properties, and become a rich source of , cosmetic moisturizing materials with good performance. Various hair shampoo and hair care products made with chitosan have the effects of being easy to comb, making hair fluffy, full to the touch, and shiny. It is more effective for fine hair that is prone to breakage and split ends. Hundreds of daily cosmetics containing chitosan are sold in Europe, the United States, Japan and other countries and regions.
Applications in the pharmaceutical industry

According to the Chinese National Pharmacopoeia (Part IV), chitosan is used as pharmaceutical excipients, disintegrants, thickeners, etc.
1. Carrier material
Using chitosan as a drug carrier can stabilize the ingredients in the drug, promote drug absorption, delay or control the dissolution rate of the drug, help the drug reach the target organ, and is anti-acid, anti-ulcer, and prevent the drug from irritating the stomach.
Chitosan can be used to prepare microspheres. The microspheres produced have good adhesion and are more suitable for administration to mucous membranes such as the mouth, nose, and gastrointestinal tract. The surface of chitosan microspheres is rich in polysaccharide chains and can be absorbed by specific cells or tissues. Through recognition, drugs can be targeted and delivered to the lesion for storage and release; functional groups can be connected to the surface of chitosan microspheres to flexibly load different drugs by adsorption or encapsulation. The drug release from chitosan drug-loaded microspheres is related to the molecular weight of chitosan. Generally, the release rate of drugs decreases as the molecular weight of chitosan increases, and the higher the concentration of chitosan, the more likely it is that the drug diffuses from chitosan into the organism. The speed of the medium is lower.
2. Film-forming materials
Chitosan can be used as a film-forming material for oral films, traditional Chinese medicine films, etc. Its relative molecular weight has a prominent impact on film-forming properties and film properties. Generally, the lower the molecular weight, the lower the tensile strength of the film and the stronger the permeability. Appropriate cross-linking agents can be selected to improve the strength of the film and change the barrier properties of the film.
3. Thickener When chitosan is used as a thickener, the viscosity of the solution increases as the concentration increases; when the concentration is high, the viscosity of the concentrated solution shows thixotropy. When the temperature increases, its viscosity decreases, and the law is consistent with the flow law of general polymer concentrated solutions.
4. Targeted preparation materials Chitosan and its derivatives can be used as targeted preparation materials. Its structural units contain functional groups such as hydroxyl and amino groups, which can be used to connect extracellular or intracellular targeting ligands to construct targeted drug carriers for targeted drug delivery treatments. There are many targeted formulations using chitosan as carrier material, mainly nanoparticles and microspheres.
5. Other applications Chitosan can be used as tablet filler and flavoring agent. Chitosan has good biocompatibility and biodegradability. The degradation products can be absorbed by the human body without accumulating in the body. It has no immunogenicity and can be made into absorbable surgical sutures.
[Cautions] It is incompatible with strong oxidants.
[Case Analysis] Fluorouracil Chitosan Microspheres
1. Preparation method
Dissolve 2g of chitosan in 100ml of 0.2mol/L acetic acid solution to prepare a chitosan solution with a mass concentration of 20g/L. According to the ratio of fluorouracil:chitosan: 1:6, weigh the corresponding amount of fluorouracil and put it into 25g of the above chitosan acetic acid solution. After stirring to completely dissolve, slowly add it to 200 ml of Span 80 containing 15 g/L and 5g/L magnesium stearate in mixed oil (vacuum pump oil: liquid paraffin = 1:4), stir thoroughly until the system becomes emulsion, maintain for 0.5 hours, add the corresponding amount of glutaraldehyde solution to the emulsion dispersion system, React at 40°C for 2 hours, adjust the pH to about 7 with sodium hydroxide solution, and continue the reaction for 1 hour. The product was separated by centrifugation, washed first with gasoline and then with absolute ethanol. Finally, vacuum drying at 50°C was performed to obtain the product.
2.Analysis
The drug fluorouracil in this preparation is slightly soluble in water. Chitosan is used as the carrier, glutaraldehyde is used as the cross-linking agent, Span 80 and magnesium stearate are used as the composite emulsifier, and vacuum pump oil and liquid paraffin are mixed to form the oil phase.
Applications in light industry
Taking advantage of the solubility and film-forming properties of chitosan, and the interconvertible chemical structures of chitosan and chitin, acetic anhydride is used as the transformation fixative of chitosan-chitin to produce a chitin-type It is a new type of fabric finishing agent that is truly formaldehyde-free (it not only retains the advantages of chitin natural polymer, but also ensures that the finishing agent and finishing process are non-toxic and harmless). Chitosan gel prepared with formaldehyde and acetic acid as cross-linking agents and chitosan as the matrix is neither soluble in water, dilute acid and alkali solutions, nor general organic solvents, and has good mechanical strength and chemical properties. Stability and other excellent properties.
Applications in environmental protection
Chitosan can interact with glutaraldehyde, and an ion exchange resin-chitosan cross-linked membrane is prepared by casting method. The resin can adsorb metal ions and can be used for industrial wastewater treatment and heavy metal extraction. Chitosan can form stable chelates through the amino and hydroxyl groups in the molecule and metal ions Hg+, Ni2+, Pb2+, Cd2+, Mg2+, Zn2+Cu2+, and Fe3+, so it can be widely used in the recovery of precious metals and industrial wastewater treatment. etc. Chitosan is used to prepare high-viscosity soluble chitosan. The resulting product has high viscosity and good quality. It is used for activated sludge treatment with excellent results. Since it is non-toxic and biodegradable, it is used for wastewater treatment and metal extraction. , will not cause secondary pollution, so it is a promising polymer flocculant and metal chelating agent.

Package and delivery

Delivery
1-80kg	80-300kg	More than 300kg
More suitable for express transportation, door-to-door	More suitable for air transportation,airport-to-airport	More suitable for ocean transportation,port-to-port
7-10 days for delivery time	3-4 days for delivery time	20-40 days for delivery time

What service we can provide
Joyous Health provides chitosan powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.

Joyous Health Factory information and certifications
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
For more details please click here

Where to buy chitosan powder?
We offer the best chitosan powder at the most competitive price. chitosan Powder bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
We also provide chitosan powder in bulk order or wholesale according to client needs. Just submit the requirements in the bottom form, we will reply soon!

Contacts: Faith Feng
Email:faith@joyouspellets.com
Tel and Whatsapp:+86 17391747738

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