• GABA sustained release pellets
  • GABA sustained release pellets

GABA sustained release pellets

γ-aminobutyric acid (GABA) is considered safe by both EFSA and FDA. In countless experiments, GABA is also considered to greatly improve sleep. However, as a functional non-protein amino acid, it is not effective in the human body. Its absorption and utilization rate is extremely low, and various digestive enzymes in the stomach can easily destroy its activity. Therefore, Joyous uses unique sustained-release pellet processing technology to make it into beautiful small pills with high absorption and utilization rate.
Product Name
GABA sustained release pellets
Appearance
white 8-12mm particles (color can be customized)
Active Ingredients
γ-aminobutyric acid (GABA)
Content
80%-90%(be customized)
Inclusion compound excipients
Ethylcellulose, HPMC, Shellac, etc.
Release time
1 hour, 4 hours, 8 hours (can be customized)
  • GABA sustained release pellets

Desciption

Product information                                                                                                                                                  
GABA sustained release pellets overview
Joyous introduced GABA sustained-release pellets based on some comparative data. As a functional non-protein amino acid, GABA needs to be decomposed in the body by the strong acid environment of the stomach and digestive enzymes. When ordinary GABA enters the body and finally reaches the small intestine, there is not much left and cannot be fully utilized and absorbed. Joyous has done some processing on GABA and adopted a drug-sustained release dosage form, which can maximize the time GABA stays in the human body. Below we will introduce it in detail
Joyous GABA sustained release pellets specification
Terms Standard Terms Standard
Product Name GABA sustained release pellets

Appearance

white 8-12mm particles (color can be customized)

Purity 80%-90%

Loss on Drying

≤2%

Total Heavy Metals

≤10 ppm

Ash

≤2%

As

≤0.5ppm

Total Plate Count

≤750 cfu/g

Pb

≤0.5ppm

Yeast and Mold

≤100 cfu/g

Cd

≤0.5ppm

Coliforms

Negative

Hg

≤0.1ppm

E.Coli

Negative

Packing

Pack in 25kgs paper-drums, inner by double plastic bag

Shelf life

24 months under the above condition, and in its original package


How are GABA sustained-release pellets made?
Joyous' GABA sustained-release pellets are made through Joyous' proprietary formulation form, controlled-release pellet inclusion technology. We mix GABA and starch, the main material of the pellet core, and completely dissolve them. When the mixture is dissolved into a uniform liquid, HPMC is added to combine, and then the particles are obtained by centrifugal suspension granulation. The particle size of the particles is controlled according to the requirements. After screening the particle size, spray shellac, and finally dissolve the coloring material into the protective layer according to the customer's favorite color, spray the color, and the final sustained-release particles are completed. After that, Joyous's quality inspection department will step in to detect the particle size through precise measurement, detect whether the content meets the requirements through the detection method of active substances (such as the internationally accepted standard detection method for GABA), and simulate the sustained release of GABA through the pulp method. The sustained release time curve of the pellets, and finally the dissolution of the active substance (such as GABA) is tested through the drug dissolution method. After the final test is completed, the GABA sustained release pellets that meet the requirements will be packaged.

GABA sustained release pellets: advantages over ordinary dosage forms and improved bioavailability
As a new dosage form of Joyous, GABA sustained-release pellets adopt advanced sustained-release technology to ensure the sustained release of GABA in the body and maintain the stability of GABA concentration in the body. Compared with ordinary forms of GABA, GABA sustained-release pellets have higher bioavailability and longer duration of drug effect.
Advantages of GABA sustained-release pellets
1. Stable release and prolonged onset of action: GABA sustained-release pellets adopt advanced sustained-release technology to ensure sustained and stable release of the drug in the body, avoid sudden increases or decreases in GABA concentration, and maintain blood concentration. Stabilize and extend the retention time of GABA in the blood.
2. Improve bioavailability: The protective layer of GABA sustained-release pellets can pass through the complex gastric environment and be continuously released in the small intestine, which can reduce the absorption burden of the gastrointestinal tract and improve the bioavailability of the drug.
3. Reduce side effects: Slower release speed can reduce irritation to the gastrointestinal tract. Generally, GABA extended-release granules allow for a lower intake than the same amount of GABA supplemented in other dosage forms. To achieve better results, this not only reduces the occurrence of side effects, but also reduces the burden on the body's kidney metabolism (because you eat less).

Comparison with other forms of GABA

1. Ordinary tablets: GABA in ordinary tablets is released quickly in the body, which can easily cause a sudden increase or decrease in concentration, affecting the efficacy and safety of GABA.
2. Ordinary capsules: Ordinary capsules release GABA quickly in the body and can easily cause concentration instability, affecting the efficacy and safety of GABA.
3. Ordinary oral liquid: GABA in ordinary oral liquid tastes better, but there is also the problem of unstable GABA concentration, and the additives in the oral liquid may have an impact on health.

Research data shows that the bioavailability of GABA sustained-release pellets is about 50% higher than ordinary tablets and about 30% higher than ordinary capsules. This means that at the same dose, GABA sustained-release granules can better meet the body's demand for GABA. This also means that using GABA sustained-release pellets, you can now take less quantity and achieve better results. This is the healthy design of Joyous.


Package and delivery                                                                                                                                                

Delivery
1-80kg 80-300kg More than 300kg
More suitable for express transportation, door-to-door More suitable for air transportation,airport-to-airport More suitable for ocean transportation,port-to-port
7-10 days for delivery time 3-4 days for delivery time 20-40 days for delivery time

What service we can provide                                                                                                                                    
Joyous Health provides GABA sustained release pellets OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.


Joyous Health Factory information and certifications                                                                                            
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
For more details please click here


Where to buy GABA sustained release pellets?
We offer the best GABA sustained release pellets at the most competitive price.GABA sustained release pellets bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
We also provide GABA sustained release pellets in bulk order or wholesale according to client needs. Just submit the requirements in the bottom form, we will reply soon!

Contacts: Faith Feng
Email:faith@joyouspellets.com
Tel and Whatsapp:+86 17391747738

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