• Mulberry Leaf extract powder
  • Mulberry Leaf extract powder

Mulberry Leaf extract powder

Mulberry leaf extract is extracted from mulberry leaf powder processed from the 1st to 3rd new leaves on the branches of mulberry trees in the late spring period or before frost. The main component is mulberry leaf DNJ. Mulberry leaf extract is suitable for treating colds. Blood sugar, blood lipids, anti-inflammatory, etc. In the supplement field, mulberry leaf extract is widely used
Product Name
Mulberry Leaf extract
Appearance
Brown powder
Specification
1%DNJ 98%DNJ
CAS No
19130-96-2
Plant Name
folium Mori
Package
25kg cardboard drum
  • Mulberry Leaf extract powder

Desciption

Product information                                                                                                                                                  
What is Mulberry Leaf extract Powder?
Mulberry leaf extract is made from mulberry leaf powder processed from the 1st to 3rd new leaves on mulberry tree branches in the late spring period or before frost. It is dried in the shade, crushed, and extracted with n-butanol, 90% ethanol and water with heating. Derived from spray drying. The extract contains mulberry leaf flavonoids, mulberry leaf polyphenols, mulberry leaf polysaccharides, DNJ, GABA and other physiologically active substances, which are used to prevent and treat cardiovascular and cerebrovascular diseases, hyperlipidemia, diabetes, obesity and anti-aging. Deoxynojirimycin extracted from mulberry leaves and flavonoids extracted from pueraria lobata combine to form a new substance - cics, which is suitable for treating hypoglycemia, blood lipids, and anti-inflammatory effects. Currently, the main specification of mulberry leaf extract is DNJ. The extraction content of DNJ is mostly 1%. There are few manufacturers that can achieve a high content of 98%. Joyous has launched high-purity DNJ for the first time.
Joyous Mulberry Leaf extract powder specification
Terms Standard Terms Standard
Product Name Mulberry Leaf extract

Appearance

Brown Powder

Purity 1%、98%

Loss on Drying

≤8%

Total Heavy Metals

≤10 ppm

Ash

≤1%

As

≤0.5ppm

Total Plate Count

≤1000 cfu/g

Pb

≤0.5ppm

Yeast and Mold

≤100 cfu/g

Cd

≤0.5ppm

Coliforms

Negative

Hg

≤0.1ppm

E.Coli

Negative

Packing

Pack in 25kgs paper-drums, inner by double plastic bag

Shelf life

24 months under the above condition, and in its original package


Mulberry Leaf extract’s main ingredients and some research results
The leaves of mulberry leaf extract contain rutin, quercetin, isoquercetin, quercetin-3-triglucoside, trace amounts of β-sitosterol, and campesterol, β-sitosterol, β-D- Glucosides, lupulin alcohol, meso-inositol, insect metamorphosis hormones achysterone and ecdysterone, hemolysin, chlorogenic acid. The volatile oil components include acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid, caproic acid, isocaproic acid, methyl salicylate, guaiacol, phenol, o-cresol, m-benzyl Phenol, eugenol, etc., and also contains oxalic acid, fumaric acid, tartaric acid, citric acid, succinic acid, palmitic acid, ethyl palmitate, triacontane, hydroxycoumarin, sucrose, fructose, glucose, aspartic acid and glutathione. Amino acids such as amino acids. And contains vitamin C - 200 to 300 mg%, glutathione 140 to 400 mg%, folic acid 105 μg%, 5-formyltetrahydrofolate 22 μg%, vitamin B1 to 460 μg%, vitamin B2 to 300 to 800% Microgram %, adenine, choline, trigonelline, as well as copper 10p.p.m., zinc 16p.p.m., boron 35p.p.m., and manganese 270p.p.m.

Joyous systematically studied the extraction and purification process of the antihyperglycemic components of mulberry leaves and came to the following conclusions:
1. The optimal extraction process of mulberry leaf polysaccharide is: purified water as solvent, solid-liquid ratio 1:15 times, reflux extraction at 90°C twice, 100rain each time. The combined extracts were concentrated and precipitated with 50% ethanol to obtain the total polysaccharide MPl of mulberry leaves, with a yield of 11.84%.
2. Use DEAE-cellulose column and Sephadex G. MP1 was further purified by 100 column chromatography to obtain
MPll, MPl2, MPl3 three polysaccharide components. Using chromatography and chemical analysis methods, the monosaccharide composition of the three components was analyzed. MPl1 is mainly composed of rhamnose, arabinose, xylose, mannose, glucose and galactose, with a molar ratio of 21:16:3. :3:1:20; MPl2 is mainly composed of rhamnose and glucose, and its molar ratio is 3:l:MPl3 is mainly composed of rhamnose.
3. The optimal extraction process of total flavonoids from mulberry leaves is: 70% ethanol, 20 times the crude drug amount, twice extracted at 85°C, 2 hours each time. The total flavonoids of mulberry leaves with a purity of 37% were obtained, and the yield was 28.1%.
4. Using the total flavonoid adsorption capacity of mulberry leaves as the evaluation index, four macroporous adsorption resins were screened, and it was found that the s-8 resin had the best adsorption and desorption performance. The adsorption capacity of total flavonoids of mulberry leaves was 31.62 mg/g wet resin. , the desorption rate is 82.69%. The dynamic adsorption performance of the resin was studied. The saturated adsorption capacity of the resin was 29.8 mg/g wet resin. The optimal precipitation process was 30% ethanol for 11 times the column volume (BV) elution and 50% ethanol for 5 times the column volume (BV). ) elution. After purification, the purity of total flavonoids obtained from mulberry leaves reached 76.63%, and the extraction rate reached 72%. S-8 resin has good regeneration performance.
5. To s. Type 8 macroporous adsorption resin and organic solvent residues of purified mulberry leaf total flavonoids extract were studied. The results showed that after pretreatment, S. Type 8 resin has basically no organic solvent residue; after purification, no organic solvent residue can be detected in the total flavonoids of mulberry leaves. It shows that the pretreatment method adopted is effective and feasible, and the treated resin can be used for the refining and purification of total flavonoids from mulberry leaves.
What are the main functions of Mulberry Leaf extract?
The main functions of Mulberry Leaf extract are to regulate blood sugar, dissipate wind and heat, clear the lungs and moisturize dryness, clear the liver and improve eyesight. It is used for wind-heat cold, lung-heat cough, headache, dizziness, red eyes and dizziness, etc.
The hypoglycemic effect of mulberry leaves is achieved through two pathways: First, the alkaloid DNJ (1-deoxynojirimycin) inhibits the activity of disaccharide-degrading enzymes, thereby inhibiting the absorption of disaccharides in the small intestine and reducing food intake. The second is to promote the secretion of insulin from β-cells through the mulberry leaf alkaloid fagomine and mulberry leaf polysaccharides, and insulin can promote the cell's utilization of sugar, liver glycogen synthesis and improve sugar metabolism, ultimately achieving Blood sugar lowering effect.
Polyhydroxynordamine isolated from mulberry leaves has strong glycosidase inhibitory effect (Asano et al., 1994); N-Me-DNJ, GAL-DNJ and fagomine can significantly reduce blood sugar levels, among which GAL- DNJ and fagomine have the strongest blood sugar lowering effects.
However, general processing and extraction methods cannot completely retain the active ingredients in mulberry leaves, because they generally use thermal processing methods, such as making mulberry leaf tea, or drying them into powder. At a certain temperature, the effective active ingredients will Greatly attenuated. Therefore, it is necessary to use freeze-drying processing technology for extraction, which can effectively preserve the active ingredients. After the raw materials are quickly frozen at ultra-low temperatures and then placed under a low pressure close to vacuum, the ice will sublime and directly change from solid to vapor. Compared with other drying methods, chemical, physical and enzymatic changes are avoided, thereby ensuring that the active ingredients of the product are less changed during storage.

Package and delivery                                                                                                                                                

Delivery
1-80kg 80-300kg More than 300kg
More suitable for express transportation, door-to-door More suitable for air transportation,airport-to-airport More suitable for ocean transportation,port-to-port
7-10 days for delivery time 3-4 days for delivery time 20-40 days for delivery time

What service we can provide                                                                                                                                    
Joyous Health provides Mulberry Leaf extract powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules, sachets, and pellets with low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.


Joyous Health Factory information and certifications                                                                                            
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
For more details please click here


Where to buy Mulberry Leaf extract powder?
We offer the best Mulberry Leaf extract powder at the most competitive price. Mulberry Leaf extract Powder bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
We also provide Mulberry Leaf extract powder in bulk order or wholesale according to client needs. Just submit the requirements in the bottom form, and we will reply soon!

Contacts: Faith Feng
Email:faith@joyouspellets.com
Tel and Whatsapp:+86 17391747738

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